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D’Andre Swift (shoulder) is inactive for Week 16.
Swift—who hasn’t played since Thanksgiving—will again be out for Detroit’s offense, but they’ll at least have Jamaal Williams back. There is still hope Swift will play over the final two games, though he might have a more limited workload alongside Williams and Craig Reynolds as the team gears up for 2022.

Damien Harris (hamstring) is active for Week 16.
Harris will return after one missed game, and he should handle a heavy workload with Rhamondre Stevenson on the reserve/COVID-19 list. In the first matchup against the Bills, Harris dominated with ten carries for 111 yards and a touchdown before the hamstring injury knocked him out for good in the second half. He’s a high-floor RB2 with greater upside for this week.

Sean Mannion has been placed on the reserve/COVID-19 list.
Dalvin Cook is on the list and will be out ten days as an unvaccinated player, so Minnesota is surely hoping Kirk Cousins—also said to be unvaccinated—isn’t eventually a positive. For today, though, Cousins is good to go, and he should be backed up by third-round pick Kellen Mond for a huge game against the Rams.

Travis Kelce (COVID-19) is out for Week 16.
Kansas City held out hope that Kelce would be cleared today, but that didn’t happen, and they’ll now be down a roster spot since they didn’t bring anyone up yesterday. The Chiefs will rely on Blake Bell and rookie Noah Gray to handle duties at tight end, though this news could mainly mean a slant towards the wideouts and running backs for Patrick Mahomes. We would be surprised if Kelce wasn’t cleared early in the week and good to go next Sunday.

Jack Doyle (ankle/knee) is out for the remainder of the game.
Doyle walked off slowly in the first quarter, but looked like he was ready to go back in, which isn’t the case. Kylen Granson should have an extended role behind Mo Alie-Cox for the rest of the night.